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Basement Membrane beneath Serous Mesothelial Cells Contains α1(IV), α2(IV), α5(IV), and α6(IV) Chains of Type IV Collagen Demonstrated by Chain-specific Monoclonal Antibodies
https://kinwu.repo.nii.ac.jp/records/96
https://kinwu.repo.nii.ac.jp/records/9602df36f9-4d5e-42ce-ad4f-bb2ac867bc1a
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
KJ00004728796.pdf (6.2 MB)
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| Item type | 紀要論文(ELS) / Departmental Bulletin Paper(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2000-12-12 | |||||
| タイトル | ||||||
| タイトル | Basement Membrane beneath Serous Mesothelial Cells Contains α1(IV), α2(IV), α5(IV), and α6(IV) Chains of Type IV Collagen Demonstrated by Chain-specific Monoclonal Antibodies | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | IV型コラーゲン | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | 基底膜 | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | 漿膜 | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | 腹膜 | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | 腹膜透析 | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | Collagen type IV | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | basement membranse | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | serous membrane | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | peritoneum | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | CAPD | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | departmental bulletin paper | |||||
| ページ属性 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | P(論文) | |||||
| 記事種別(日) | ||||||
| 値 | 原著 | |||||
| 記事種別(英) | ||||||
| 言語 | en | |||||
| 値 | Original Paper | |||||
| 論文名よみ | ||||||
| その他のタイトル | Basement Membrane beneath Serous Mesothelial Cells Contains α1(IV), α2(IV), α5(IV), and α6(IV) Chains of Type IV Collagen Demonstrated by Chain-specific Monoclonal Antibodies | |||||
| 著者名(英) |
Naito, Ichiro
× Naito, Ichiro× Matsubara, Tatsuya× Takahashi, Chieko× Ohmori, Hiroyuki× Sado, Yoshikazu× Ninomiya, Yoshifumi× Okigaki, Tohru |
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| 著者所属(英) | ||||||
| 言語 | en | |||||
| 値 | Division of Ultrastructual Biology, Shigei Medical Research Institute | |||||
| 著者所属(英) | ||||||
| 言語 | en | |||||
| 値 | Division of Internal Medicine, Shigei Medical Research Hospital | |||||
| 著者所属(英) | ||||||
| 言語 | en | |||||
| 値 | Division of Ultrastructual Biology, Shigei Medical Research Institute | |||||
| 著者所属(英) | ||||||
| 言語 | en | |||||
| 値 | Division of Internal Medicine, Shigei Medical Research Hospital | |||||
| 著者所属(英) | ||||||
| 言語 | en | |||||
| 値 | Division of Immunology, Shigei Medical Research Institute | |||||
| 著者所属(英) | ||||||
| 言語 | en | |||||
| 値 | Department of Molecular Biology and Biochemistry,Okayama University School of Medicine | |||||
| 著者所属(英) | ||||||
| 言語 | en | |||||
| 値 | Department of Social Welfare, School of Social Welfare, Kinki Welfare University | |||||
| 抄録(英) | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Serous membrane (SM) covers inner surface of abdominal, thoracic and pericardial cavities, aswell as outer surface of organs inside the cavities. It consists of surface mesothelial cells andloose connective tissue. Between them, a thim layer of basement membrane (BM) is located. Type IVcollagen is major constituent of BM, and consists of 6 different a(IV) chains, a1(IV) through a6(IV).Chain-specific functions are assumed by a chain-specific manner of localization. The a(IV) chaincomposition of skin, covering outer surface of the body, is demonstrated to have a1(IV), a2(IV), a5(IV),and a6(IV) chains, whereas that of SM, covering inner surface of the body, is yet to be analyzed. Abdominal wall, small intestine, thoracic wall, lung, pericardium and epicardium of humanmaterials were used in this study. Chain-specific monoclonal antibodies (mAbs) used were H11(for a1), H22 (for a2), H31 (fo a3), H43 (for a4), H53 (for a5) and H63 (for a6). Fresh frozen sectionswere stained with indirect immunofluorescence staining using the mAbs. Four out of six a(IV) chains, a1, a2, a5 and a6, were demonstrated in BM beneath themesothelial cells of all types of SMs, whereas only capillary BM consisted of a1 and a2. Besides,epicardial SM expressed a3 and a4 moderately as extra components. The a(IV) chain composition was same as those of epidermal skin BM. Therefore, these a(IV)chains are designated to be essential for BM covering inside and outside of the body. | |||||
| 雑誌書誌ID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA11887920 | |||||
| 書誌情報 |
近畿福祉大学紀要 巻 1, p. 20-25, 発行日 2000-12-12 |
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